|QbD is Coming!
Good news of course. A quality driven understanding of every aspect of your process will assure a higher standard of drugs, treatment and
diagnostics. But with it comes the need to evaluate, understand and control the sources of degradation, variability and inefficiency at every step in
your process. With estimates claiming that one out of three clinical errors originate from preclinical handling errors, heavy scrutiny will undoubtedly
be applied in these areas. Thawing has long been overlooked as a source of such errors. Yet recent studies reveal what we all could have
guessed: Degradation and variability can be introduced through haphazardly transitioning samples from deep freeze to working temperatures.
Both time and temperature have a range of measurable impacts. Using water baths can introduce pathogens and contamination. Furthermore
they introduce random and potentially harmful heat cycles in the process of trying to hold in a bath full of frozen samples at set temperature. Heat
blocks pose similar risks. And the old "tube in the pocket" method, well, that's not going to make the cut either.
BOX Scientific's all purpose thawing solutions can help you make the most of the time, money and pride you have put into your laboratory
operations. Clean and nearly maintenance free they work in concert with your existing environmental controls to produce fast, safe and consistent
thawing. They are free of the risks of contamination and heat, yet provide fast, reproducible results that fit within the most stringent quality
guidelines. This highly reproducible thawing can be proceduralized and validated to produce a new and measurable level of control. That is what
you call Quality by Design. We call it Achieving Equilibrium!
|Our thaw systems help maintain
throughput without putting delicate
samples or expensive reagents at risk.
They're priced to fit your consumables
budget and offer great ROI. Our negligible
power consumption won't become an
investment of its own either.
|The literature is consistent. Freeze thaw is
a known degradant and faster thawing is
the best damage control. Our thaw stations
fit within all existing FDA freeze-thaw
guidelines and provide you a fixed platform
for procedural thawing under GMP, GLP
and more. You put a lot of effort into
process and environmental controls. Now
you can shorten your thaw intervals while
assuring consistent sample and reagent
is providing ever
gains. Why lose time
waiting for samples to
thaw on a bench or in a
Our thaw systems are
fast, maintenance free
and designed to fit most
automation and liquid
handling labware from
1-50ml. More efficiency,
We really do feel our thaw station units represent a new paradigm. They fit within FDA guidelines for "unassisted thawing" yet
reduce thaw times up to 75% over benchtop thawing. And their fixed mode of operation allows for ease of use as well as
procedural thawing under GMP/QSR, USP, ISO etc. Having a freezer monitored 24 hours a day and complex SPC around your
process is of little use if you are not applying comparable control measures in between. Procedural thawing is the inevitable
future in an increasingly regulated and automated life science landscape.
Ready to Achieve Equilibrium?
Contact us today for a more information or to schedule a demo.
|All Box Scientific products are proudly made right here in the USA under GMP guidelines. |